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Sekisui Diagnostics chromogenic substrate spectrozyme fxa
Chromogenic Substrate Spectrozyme Fxa, supplied by Sekisui Diagnostics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/chromogenic+substrate+spectrozyme+fxa/chromogenic+fxa+spectrozyme+substrate/pm42273738-223-1-5
Average 86 stars, based on 1 article reviews
chromogenic substrate spectrozyme fxa - by Bioz Stars, 2026-10
86/100 stars

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Related Articles

Concentration Assay:

Article Title: Discovery and optimization of marstacimab, a human monoclonal antibody targeting tissue factor pathway inhibitor for the treatment of hemophilia A and B.
Article Snippet: Human plasma-derived FXa (2 nM; Haematologic Technologies, catalog no. HCXA-0060) was introduced, and the reactions were incubated at 37°C for 30 min. .. The chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics LLC, catalog no. 222) was added to reach a final concentration of 500 μM to each well for a final reaction volume of 100 μL. ..

Article Title: Discovery and optimization of marstacimab, a human monoclonal antibody targeting tissue factor pathway inhibitor for the treatment of hemophilia A and B.
Article Snippet: Lipidated tissue factor, 1 pM (Innovin, catalog no. 23–044-776) and 1 nM recombinant FVIIa (NovoSeven, Novo Nordisk) were added to the reactions and incubated at 37°C for 5 min. Human FX, 150 nM, (Haematologic Technologies, Inc. catalog no. HCX-0050) was introduced into the reactions. .. The chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics LLC, catalog no. 222) was added to a final concentration of 500 μM to each well for a final reaction volume of 100 μL. ..

Activity Assay:

Article Title: Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling
Article Snippet: TF activity was determined by adding 0.5 mL HBS containing human FVIIa and 50 nM FX (Haematologic Technologies, Essex Junction, VT) to adherent cells per 12-well plate at 37°C. .. Activity of FXa was measured in 0.1M EDTA-quenched samples with the chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics, Stamford, CT) by using a kinetic plate reader (Spectramax M2, Molecular Devices). ..

Purification:

Article Title: Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis
Article Snippet: .. Purified TAP fusion constructs were characterized for their ability to inhibit FXa in solution using chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics). ..

Article Title: Platelet-targeted thromboprophylaxis with a human serum albumin fusion drug: Preventing thrombosis and reducing cardiac ischemia/reperfusion injurywithout bleeding complications
Article Snippet: .. The inhibition of FXa by the purified proteins was determined using the chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics, USA), as per the manufacturer's instructions. ..

Construct:

Article Title: Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis
Article Snippet: .. Purified TAP fusion constructs were characterized for their ability to inhibit FXa in solution using chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics). ..

Inhibition:

Article Title: Platelet-targeted thromboprophylaxis with a human serum albumin fusion drug: Preventing thrombosis and reducing cardiac ischemia/reperfusion injurywithout bleeding complications
Article Snippet: .. The inhibition of FXa by the purified proteins was determined using the chromogenic substrate Spectrozyme FXa (Sekisui Diagnostics, USA), as per the manufacturer's instructions. ..



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